
Adipokines in Obesity
Adipose tissue is the source of soluble mediators (adipokines), secreted mainly by adipocytes. Leptin actson the brain and peripheral organs to regulate energy homeostasis and the neuroendocrine axis.Adiponectin regulates glucose and lipid metabolism by targeting the liver and skeletal muscle. Adiposederivedproinflammatory cytokines, vasoactive peptides, coagulation and complement factors, visfatin,vaspin and retinol-binding...