Obesity and BBS
Obesity is a cardinal aspect of the BBS phenotype, beginning in early childhood andprogressing with age; it is usually associated with the trunk and proximal limbs. A surveyof UK BBS patients identified 72% of adults as overweight (BMI 25) and 52%defined as obese (BMI 30) . At present, the physiological and biochemical abnormalitiesunderlying obesity in BBS are poorly understood. A case-control studyshowed no significant differences...
